Dissolved oxygen, pH value, conductivity, temperature, etc. are key factors for analyzing water quality. And, how to measure the key factors real-timely is particularly important. It is impossible for traditional empirical methods and chemical detection to satisfy production requirements today. However, with the development of intelligent and networked sensors, wireless network technology can satisfy the requirements of accuracy and real-time in water quality monitoring. ZigBee technology not only has characteristics of short distance, low complexity, powerful networking capability, low cost and high stability, but also has self-owned wireless transmission standard in which multiple modes which can relay each other achieve effective communication in measuring nodes, which fully meets the needs of the wireless water quality monitoring. This paper puts forward wireless water quality monitoring system based on JN5139 ZigBee wireless module. The system gathers perception module, micro-control module and wireless transmission module. Multiplex water quality parameters are collected periodically by wireless network, stored and finally displayed on host computer. These data can also be checked by users after connecting JN5139-Z01-M02/4 system through computer. In case of buildings, trees and obstruction, distance accuracy is 100 m at least. According to experiments, the system has high scalability, low power consumption, strong stability and so on, which can meet the requirements of real-time and data accuracy in water quality monitoring.