Underground drip irrigation is the best way of aerated irrigation, but the narrow channel of the dripper is easy to be clogged by particles in the water. It is of great significance to improve the operation efficiency of aerated drip irrigation system if the law of fine sediment transport and deposition under aerated conditions can be found out and reasonable control measures can be taken to alleviate dripper clogging. In order to explore the influence of aeration on the dripper clogging, five kinds of sediment graded muddy water (0～0.100mm, 0.075~0.100mm, 0.050~0.075mm, 0.031~0.050mm and 0～0.031mm) with sediment concentration of 1g/L were disposed and the effect of aeration in water on the toothed labyrinth channel dripper clogging was studied by periodic intermittent irrigation test. The deposited sediment was observed and analyzed by laser particle size analyzer and field emission scanning electron microscope. The results showed that aeration and sediment particle size had significant effect on dripper clogging (P<0.01). Aeration improved the sediment transport capability in the laterals, promoted the discharge of large particle sediment, reduced the median particle size of depositing sediment and the effect of aeration on sediment transport was decreased with the decrease of the maximum particle size of sediment. The mass of depositing sediment and the median particle size of depositing sediment in the laterals were 8.75%～31.92% and 8.59%～35.64% lower than those without aerated treatment. When the particle size was 0.075~0.100mm, the relative flow rate of the dripper was decreased the fastest and the relative flow rate of the dripper was decreased the slowest when the particle size was 0～0.100mm. Aeration enhanced the degree of flow turbulence and promoted the transport of large-particle sediment in the flow channel. Aeration promoted the adhesion of small-particle sediment at the entrance of the flow channel and accelerated the clogging of the flow channel entrance. The Dra and Cu of dripper were 9.0～18.7 percentage points and 16.2～36.4 percentage points lower than those without aerated treatment. The above were the main reasons for aeration aggravates the clogging of the dripper. It was suggested that lateral flushing should be carried out to reduce the risk of channel entrance clogging and improve the anti-clogging capability of aeration drip irrigation dripper.