Aiming at the problems in the combine harvester manufacturing industry, including the low automation level of the combine harvester manufacturing quality inspection, the lack of a complete inspection system and other problems, combined with relevant national standards and the actual needs of the enterprise, two kinds of combine harvester manufacturing quality inspection plans were proposed, one was multistation pipelined inspection system, the other was multifunctional cellline inspection system. The virtual models of the two combine harvester manufacturing quality inspection systems were established through digital means, the models included combine harvester, inspection equipment and instrument, sensors, workshop and virtual workers. The two inspection systems were simulated in the Visual Components environment respectively to analyze the applicable scope, work intensity, the efficiency of the equipment and instrument, and other workshop operation parameters. And the simulation results showed that the multifunctional cellline inspection system was more suitable for combine harvester manufacturing quality inspection. On the basis of modeling and simulation, with the electrical system of combine harvester as the object, a set of inspection system based on virtual instrument technology was developed to realize the fast testing of the electrical working conditions, starting performance and other working parameters, which improved the inspection efficiency. The research results show that the construction of digital workshop simulation model can provide effective evaluation methods for inspection process evaluation and system development, thereby providing strong support for manufacturing process optimization. 