A calculation model of jet hole arrangement ways was established based on the characteristics of single jet hole. With SST kω turbulence model, the drag reduction characteristics of jet surface under the condition of different jet hole arrangement was researched by using the numerical simulation. Then, the impact of jet hole arrangement on surface viscous resistance and drag reduction rate was analyzed, and the maximum drag reduction rate reached 33.65%, which was experimentally validated by using numerical calculation model. The movement characteristics and distribution rules of the shear stress of wall boundary layer, the surface compressive stress, the flow velocity and vortex generating in the downstream of the jet hole were studied. The results showed that wall boundary layer could be well controlled by jet hole arrangement of jet surface, and the drag reduction mechanism of jet surface was also revealed.