In order to meet the control reliability requirement of hybrid vehicle electronic shift handle signal, based on analyzing the structure and signal control logic of the handle, the reliable control method was designed by signal processing and strategy redundancy algorithm. Through the establishment of the system control model with Simulink and the usage of rapid control prototyping approach with MotoTron, the control method of the shift handle signal was tested to verify its reliability. Test results showed that the control method could meet the shifting demand for hybrid vehicle, and the control reliability of the shift handle signal and traffic safety could be ensured. 