Multi-sensor signals acquisition and data processing is the basis for combine harvester workflow control and monitoring. In this paper, the multi-hall speed sensor signal acquisition was implemented by timer/counter and standard input/output interface (I/O) in microprocessor C8051F020, and feed quantity sensor data and loss quantity sensor data was received through the serial communication. Microprocessor C8051F020 can process and save data, control the 240×128 dot-matrix LCD that could display the current data and fault alarm, and control speed depend on the results of data processing, then deal with classified faults. The data acquisition could be send and print. The experimental result showed this system worked steadily and reliably, which could realize the integration of combine harvester workflow control and monitoring system, and it could save the production cost and increase efficiency for combine harvester measure and control system.