For a certain engineering vehicle roll in the sloped area, the finite element model and multi-rigid-body model were developed based on the nonlinear finite element method and multi-rigid-body approach, respectively. The dynamic simulations were performed. The deflection and absorbed energy were predicted, the dynamic response and injury risks of the operator during lateral roll were also predicted. Results showed that the roll-over protective structure (ROPS) and energy-absorbing device could prevent the vehicle continuous roll on the slopes with small angles and reduce the plastic deformation of ROPS. The severity of the peak decelerations transferred to the vehicle cabin was also reduced simultaneously. 