Aiming at the existing sandwich seaweed production equipment uses a single piece of seaweed to process and produce one by one，there are many problems，such as too many dropped sandwich materials，and it is difficult to accurately align two pieces of seaweed，resulting in serious material waste，poor product quality，and low production efficiency，thus a processing method of bonding a single sheet of seaweed into a ribbon-shaped seaweed sheet by hot pressing bonding was pioneered，and the experimental research and parameter optimization of the hot pressing bonding process of this seaweed sheet was carried out. Firstly，the effects of hot pressing temperature，hot pressing time and alcohol concentration on the toughness and adhesion of the bonded seaweed sheet were studied by single factor experiment. Then，through quadratic regression orthogonal test and response surface analysis，the influence law of each factor on the evaluation index was studied，and the mathematical model between each influencing factor and the evaluation index was established. Finally，through the solution of the mathematical model，the hot pressing bonding process parameters of seaweed tablets were optimized，and the optimization results were verified by experiments. The test results showed that hot pressing temperature，hot pressing time and alcohol concentration had significant effects on the toughness and adhesion of seaweed sheets (P<0.01). With the increase of hot pressing temperature，the toughness of seaweed sheets was decreased and the adhesion was increased. With the increase of hot pressing time，the adhesion was increased，but the toughness was decreased first and then increased. With the increase of alcohol concentration，the toughness of seaweed sheets was decreased gradually，and the adhesion was firstly increased and then decreased. By optimizing the experiment parameters，the optimal combination of parameters was determined：hot pressing temperature was 208.39℃，hot pressing time was 2.91s，alcohol concentration was 61.52%，at this time，the toughness of seaweed sheet was 8.86N·mm，and the adhesion force was 1.36N. The validation test showed that the test results were basically consistent with the optimization results，indicating that the established parameter optimization model was reliable and the optimized parameters met the processing requirements of seaweed sheets. The research results can provide theoretical and technical support for the processing method of sandwich seaweed.