In view of the problem that excessive wheat straw residues blocked the furrow opener in the no-tillage sowing operation in Huang-Huai-Hai region, an oblique anti-blocking device was proposed to achieve the cleaning of the seedling bed in the form of dial-off stubble and shallow rotation stubble. The structural parameters of the anti-blocking device were designed to determine the stubble clearing width, tillage spacing, knife shaft position and inclination range. According to the device structure, the force analysis of the plough blade in the anti-blocking process was carried out to determine the factors affecting the working performance. Through the discrete element simulation of anti-blocking device in the field operation process, taking straw cleaning rate, soil disturbance coefficient and power consumption as evaluation indexes, regression analysis and significance test were carried out on the inclination angle, revolution speed and forward speed of the device, and the influence of various factors on the evaluation index and the primary and secondary order were determined. The order of influence on straw clearance rate and soil disturbance coefficient was inclination angle, forward speed and rotational speed, and the order of influence on power consumption was inclination angle, rotational speed and forward speed. Through the multi-objective function optimization of the regression model, the optimal combination of parameters was obtained as follows: rotational speed of 400r/min, forward speed of 6km/h, inclination of 18.5°, and the straw clearance rate was 74.5%, the soil disturbance coefficient was 34.7%, and the power consumption was 1.36kW. The soil bin test was carried out on the device with the optimized parameters to verify the working performance of the anti-blocking device. The test results showed that compared with the inclination angle of 0°, when the rotational speed was 400r/min, the forward speed was 6km/h, and the inclination angle was 18.5°, the straw clearance rate and the straw side throw were improved, the soil disturbance coefficient was increased, the moving soil rate was increased, the soil backfill rate was decreased, the power consumption was increased, the three-axis resultant force was decreased, and the three-axis resistance was increased. At this time, the straw clearance rate was 92.5%, the soil disturbance coefficient was 29.6%, and the power consumption was 1.51kW. The test results were consistent with the optimization results of the simulation test, which met the design requirements.