Nutrient solution configuration and irrigation control technology have become the key technology in soilless culture. However, the current nutrient solution management control has problems such as cumbersome configuration process, inaccurate nutrient solution ratio and single irrigation strategy, which hinder the development of soilless culture technology. Aiming at the above-mentioned various problems, nutrient solution management and control system was designed based on the Mariotte device. The system was mainly composed of nutrient solution preparation system and nutrient solution irrigation control system. Through EC (conductivity) value and pH value sensors, the components of the nutrient solution were obtained in real time, the mathematical model of liquid preparation and prescription was established, and the target nutrient solution was automatically and quickly configured according to the nutritional needs of different crops. According to the needs of different users, combined with the meteorological parameters and application environment of the crop cultivation area, three different irrigation strategies were formulated. Experiments showed that the system can quickly and accurately realize the management and control of the nutrient solution, laying a part of the foundation for the production of soilless cultivation of crops. 