During the field of selfpropelled sprayer, due to the large quality and volume of whole vehicle and its working on the complex and diverse road, which lead to the selfpropelled sprayer prone to slip, and requires an antiskid control strategy to maintain stable driving of the machine. For this reason, a fuzzy antiskid control strategy and controller was proposed. Based on the control system, the simulation analysis of the controlling system was carried out by Matlab/Simulink, the simulation result showed that the fuzzy antiskid control system can effectively control the slip rate at the ideal of 0.05. Finally, the performance of the driving antiskid control system was verified through field tests. The result of the experiment showed that when the design of the fulltime fourwheel drive hydraulically driven sprayer fuzzy antiskid control device was traveling at low speed, the average slip rate was 0.078 with the situation of without antiskid control. By contest, when the opening of the antiskid the average slip rate was 0.028; when the selfpropelled sprayer traveling with a medium speed and the antiskid control was closed, the average slip rate was 0.109. However, when the antiskid control was turned on and the average slip rate was 0.031; when the selfpropelled sprayer traveling with a high speed and the antiskid control was closed, the average slip rate was 0110, but the average slip rate was 0.035 after it was opened. Above experiments indicated that the control system had a good antiskid control effect. The research results provided a theoretical basis for the antiskid control of fourwheel drive hydraulically system of selfpropelled sprayer.