The relationship between grain yield response of winter wheat and soil water under different soils was simulated based on the calibrated Aquacrop model, and the expansion at regional scale was conducted to the results from the model simulation, combined with the soil distribution and the actual planting of winter wheat in Daxing District, Beijing, on the basis of which the variations of the water consumption, the yield and the water productivity of winter wheat under different irrigation schedules were analyzed, and the deficit irrigation schedule for winter wheat that was suitable for the actual situation of the water resources in North China was recommended. The results showed that the application of Aquacrop model can better simulate the dynamic changeable process of the soil moisture and the canopy coverage during the growth period of winter wheat as well as the biomass and the yield, and the calibrated model can be used to study the relationship between grain yield response of winter wheat and soil water. When the irrigation quota was within the range of 300mm, the water consumption was increased with the increase of irrigation amount;under the condition of the same number of irrigation times, the difference of the water consumption was significant due to the variation of the transpiration amount since the irrigation date was different. Under the same treated conditions, the yield was higher in the years with excessive precipitation on the whole, while the yield was increased with the increase of irrigation amount under different treated conditions;with the same irrigation times, the selection of irrigation date for key growing stage was essential to the yield formation of the winter wheat and the increase of water productivity. Based on the principle of production-increasing and efficiency-improving of the winter wheat, in the case of the irrigation for one time, the key guarantee should be on the water demand for the jointing-heading-stage;in the case of the irrigation for two times, the key guarantee should be on the water demand for the returning-green-jointing stage and heading-milky-ripe-stage;in the case of the irrigation for three times, the key guarantee should be on the water demand for the returning-green-jointing stage, the jointing-heading-stage and the heading-milky-ripe-stage. Aiming at the actual situation of the serious shortage of water resources in North China, it was recommended that the deficit irrigation schedule with two times of irrigation should be adopted for the winter wheat in Daxing District, Beijing, which can reduce the irrigation quantity and water consumption respectively by 140mm and 65mm to ensure 75% of the yield, compared with the condition of the irrigation for four times. Thus it can be seen that the selection of proper deficit irrigation schedule can greatly reduce the regional irrigation amount and water consumption in the areas of shortage of water resource similar to North China, which had important practical significance in stabilizing the yield of winter wheat and conserving water sources in the region.