An experiment was carried out to study irrigation schedule based on moisture and electric conductivity (EC) sensors in cucumber production based on organic culture. Coconut bran was the substrate of cultivation. Three irrigation strategies were implemented which was scheduled by digital timer (CK), moisture sensors (T1), as well as moisture and EC sensors together (T2). Coir moisture content, EC of input nutrient solution and drainage were monitored, which was used to determine irrigation volume. The growth parameters were measured, including SPAD value of leaves, stomatal conductance, photosynthetic rates, fruit quality and yield, as well as irrigation amount, and production efficiency of consumed nutrient solution was calculated. The results showed that under the three irrigation strategies, difference in plant growth, yield and quality of harvested cucumber was insignificant. Total irrigation amount of T2 was 49.08% less than that of CK, and 31.85% less than that of T1. Use efficiency of nutrient solution of T2 was 103.92% higher than that of CK and 60.59% more than that of T1, respectively. In conclusion, the irrigation strategy based on incorporated application of moisture and EC sensors offered better nutrient solution use efficiency. The strategy can be used in automatic management of nutrient solution supply in organic culture of cucumber in greenhouse.