The depth of flow path of drip irrigation emitter is important geometrical parameter to anti-clogging performance. An Eulerian-Lagrange liquid-solid multiphase turbulence model combined with the kinetic theory of granular flow was used to carry out simulation based on coupled CFD-DEM water-sand two-phase flow in drip irrigation emitter with labyrinth channel. The trajectories and speed of single sediment, speed of sediment group, moving pattern and distribution of sediment group were analyzed. Simulation result indicated that the quantity of sand near the central plane of depth was more than that near the wall. The volume concentration of sediment in channel was increased several times with the decrease of depth. The depth was small;the speed of waterflow in depth direction was descended, but the speed of sediment in depth direction was risen. The average number of hit of each sediment was 14.31 when the depth was 0.6mm, but the number was 2.04 when the depth was 1.4 mm. The increase of impact frequency to wall changed original movement direction of sediment, augmented the number of times of collision between sands and between sand on the wall, which decreased velocity and kinetic energy, and it was difficult for sand to go through labyrinth channel, which caused clogging easily. This method was applied to analyze movement and distribution of sand individuality and group, learn the movement regular from micro-view perspective, and it had become an efficient technique in structure design of labyrinth channel.