The yield and quality of arabica coffee cannot be guaranteed because of serious contradictory of water and heat, soil impoverishment and serious seasonal drought in Yunnan dry-hot valley. The objective of the research was to explore water and fertilizer management mode for good quality and proper yield of arabica coffee. Four levels of irrigation in dry season, i.e., sufficient irrigation level (W 1 ) and three deficit irrigation levels (W 2 , W 3 and W 4 ), were designed with irrigation amounts for W 2 , W 3 and W 4 as 80%, 60% and 40% of W 1 , respectively, and three levels of nitrogen, i.e., N 1 (140 g/plant), N 2 (100 g/plant), N 3 (60 g/plant), were applied. The effect of drip irrigation and nitrogen levels on yield, quality and water use efficiency (WUE) of arabica coffee was studied by field experiments for two consecutive years, and the comprehensive nutritional quality was evaluated by principal component analysis. The results showed that compared with W 4 treatment, improving irrigation amount increased dry bean yield and chlorogenic acid of dry bean by 42.8%～151.0% and 16.9%～31.5%, respectively. WUE was firstly increased and then decreased with irrigation amount, WUE of W 2 treatment was the largest. Improving nitrogen application rate increased dry bean yield, WUE, protein and chlorogenic acid of dry bean by 32.9%～42.6%, 32.0%～45.8%, 5.9%～9.7% and 7.0%～12.6%, respectively, and the yield of dry bean and WUE of N 2 were the largest compared with N 3 treatment. Compared with W 4 N 3 treatment, improving irrigation amount and nitrogen application rate could increase dry bean yield and WUE by 22.0%～307.5% and 18.2%～205.3%, respectively. W 1 N 2 treatment obtained the largest average dry bean yield of 5 587.42 kg/hm 2 in two years. Principal component analysis showed that the comprehensive nutritional quality of W 2 N 2 treatment was the best, and in coordination between water and nitrogen resulted in decrease of yield and quality. Compared with W 4 N 3 , W 2 N 2 treatment increased dry bean yield and WUE greatly, meanwhile it increased protein and chlorogenic acid but reduced fiber of dry bean significantly. On the basis of water-saving and high efficiency along with good quality and proper yield, the suitable mode of water and nitrogen management of arabica coffee was the combination of W 2 and N 2 treatments (W 2 N 2 ) in arid-hot area.