In order to promote the application of low-temperature pasteurization in the heat thermosensitive materials, the equipment was designed. The design principle, its structural characteristics and processes were proposed, and the thermal power, heat transfer and flow resistance were analyzed. The maximum processing capacity was 13800mL/h with 230mL/min of maximum flow velocity. Taking water as treatment material, the temperature of water can reach to 52℃ from 4℃ in 4.5s, and reduce to 20℃ from 52℃ in 3s or 10℃ in 6s. And the bacterium concentration of liquid egg white could lessen to 100CFU/mL in 2.5min at 55℃. The performance test shows that the system possesses a good heat-transfer capability, and a high sterilizing effect. Results provide the technical basis for the design and manufacture of low-temperature pasteurization equipment.