Simulating models of air-velocity distribution and droplets deposition were developed based on CFD technology. The simulation boundary conditions and model variables were defined according to the working parameters measured from the mist-sprayer. Based on these models, air-velocity distribution characteristic and droplets deposition pattern were obtained on various simulation condition such as different air-assisted velocities and nozzle installation angles. The relative errors of simulated results were confirmed through corresponding experiments on the same condition. The result showed that air-velocity distribution of the mist-sprayer was more advantageous to obtain better effect of droplet deposition when the nozzle installation angle was in the range of 5° to 10°.