Daxing distict of Beijing was selected as the study area, the effect of agricultural water-saving measures on the quantity of groundwater extraction and recharge was studied by rejusting irrigation water supply rates and irrigation water supply rates based on the calibrated water balance model. The main results were as follows: when irrigation water supply rates decreased and water use efficiency increased, groundwater extraction was decreased significantly in different hydrological years. When irrigation water supply rates decreased, the net groundwater extraction was decreased much more than when irrigation water use efficiency increased. The sensitivity analysis showed that irrigation water supply rate is much more sensitive variable to the groundwater extraction. On the other hand, irrigation water use efficiency is much more sensitive to groundwater recharge. Within the value of index level selection, the variation of irrigation water supply rate is much more sensitive to groundwater extraction and exchange. With the increace of irrigation water use efficiency, the sensitivity to groundwater extraction and exchange is decreased. Therefore, compared with the increase of irrigation water use efficiency, the decrease of regional irrigation water supply rates is much better to promote regional water resource continuously and effectively as well as to reduce groundwater extraction for water shortage region under any water-saving condition.