In order to meet the need of multi-sensor information collection in the autonomous navigation control system for combine harvester, an information collection control network was designed. A distributed control network with two serial ports and CAN bus was designed. Two serial ports were used to collect the data from the GPS and the inertial sensor. Multi-threading programming technology could satisfy the need of the real time and multi-tasking. The CAN bus communication protocol was designed to make the network ordered and reliable. The experiment results showed that the system worked well and the communication between the sensors to the PC was reliable.