The two non-linear mount simulation models were created by using Matlab software to fit various mount experiment data based on co-simulation. The vibration isolation characteristics of automobile powertrain system was studied under ADAMS software environment along with transmitting data through information exchange interface, and different mounts’vibration isolation performance was analyzed, which could provide research foundation for optimizing analysis and matching of mount system. The results show that the vibration characteristic of powertrain system is closer to actual situation founding on non-linear mount model than on the linear.