The cereal and oil food supply chain is characterized by long full life cycle, complicated links, diversified hazardous materials and multisource heterogeneous information. The cereal and oil food full supply chain information security management prototype system based on blockchain was put forward, which stored and managed the multisource heterogeneous cereal and oil food supply chain information via the tamperproof and informationtraceable features of blockchain. Through business process analysis of cereal and oil food supply chain, its newtype information security management model was built based on blockchain technology, the dualmode data storage mechanism suitable for it was studied and proposed, the supply chain data was stored by the combination of blockchain storage and offchain database storage. In addition, the supply chain information was managed through the smart contract, ensuring the security and credibility of information storage and transmission. Afterwards, based on Hyperledger Fabric, the system architecture of cereal and oil food full supply chain information safety management prototype was designed, thus realizing the functions of its information collection, query, monitoring and traceability. At last, the system was realized based on Browser/Server network structure. Besides, through the verification and analysis of specific application cases, it can provide a new solution and reference for the quality and safety of cereal and oil.