2.608MPa。Particles of rice straw processed by sodium hydroxide can be used as binder in biomass fuel. The quadratic orthogonal rotation design with three factors was used to study the effects of the mass fraction of NaOH, temperature, and reaction time of alkali treatment on shear bond strength. Functional models of shear bond strength with three factors were established and analyzed by regress method in SPSS13.0 and response method in Matlab 7.1. The results show that the regression equation was effective, and the mathematical model for the simulation was presented. The effect order of three factors was as follows: the processing temperature, the amount of consistency, reaction time. The optimum conditions were 1.5% of consistency, 95℃ of temperature and 17h of reaction time.