Solid acid catalyst can be applied to the transterification as a substitute of homogeneous acid catalyst. Zr-modified solid super acid S2O2-8—TiO2/Fe3O4 was prepared as the catalyst for FAME production and the catalysis activity was studied by single-factor and orthogonal experiments. The results show that the esterification rate and product yield can realize to 94% and 90% respectively when the volume to mass ratio of methyl alcohol to acid is 3mL/g, the reaction temperature is 65℃, the reaction time is 6h, and the amount of catalyst is 12％ of mass of fatty acid. The recovered catalyst can be reused effectively.  