65%。To study the effects of different parameters such as initial C/N ratio, aeration rate and initial water content on volatile solid reduction, relative heat generation HR and the continue time t of the compost temperature above 50℃ during pig slurry-wheat straw composting, the successive single factor composting tests and the orthogonal composting tests were carried out to optimize the composting process, respectively. The dry wheat straw was chosen as bulking agent, successively single factor composting tests were conducted on with the initial C/N ratio of 20, 25, 30 and 35, with the aeration rate of 0.18, 0.26, 0.34 and 0.42 L/(min?kg), and with the initial water content of 55%, 60%, 65% and 70%, respectively. Based on the single factor tests, the orthogonal composting tests of L9(34) were designed. The experimental results showed that the initial C/N ratio had obvious influence on volatile solid reduction rate ηand HR, especially on t, but the aeration rate and water content had not. According to the results of orthogonal composting tests, the optimal parameters for pig slurry-wheat straw composting were obtained as the initial C/N ratio of 20, the aeration rate of 0.34 L/(min?kg)and the initial water content of 65%. 