Calibration is an important step of the automobile electronic control unit development. Since more and more ECUs have been applied in automobiles, a multi-ECUs calibration system will help to match and optimize these ECUs' parameters better. An interface between TouCAN module and CAN bus was developed. On the basis of CCP, by configuring the slave stations addresses, the ID of receive/transmit buffers, bit timing registers and receiving global mask registers of TouCAN, the communication between several ECUs and calibration of them were realized. The efficiency of calibration was well improved.