傅玉颖,李可馨,王美,沈亚丽,陈国文,李欣.GA—zein复合纳米粒子运载姜黄色素体系的制备与特性[J].农业机械学报,2017,48(1):267-274.
FU Yuying,LI Kexin,WANG Mei,SHEN Yali,CHEN Guowen,LI Xin.Preparation and Characteristics of Curcumin-loaded GA—Zein Composite Nanoparticles[J].Transactions of the Chinese Society for Agricultural Machinery,2017,48(1):267-274.
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GA—zein复合纳米粒子运载姜黄色素体系的制备与特性   [下载全文]
Preparation and Characteristics of Curcumin-loaded GA—Zein Composite Nanoparticles   [Download Pdf][in English]
投稿时间:2016-05-26  
DOI:10.6041/j.issn.1000-1298.2017.01.035
中文关键词:  玉米醇溶蛋白  姜黄素  阿拉伯胶  纳米粒子  包埋
基金项目:浙江省重中之重一级学科开放基金项目(JYTsp20141103)
作者单位
傅玉颖 浙江工商大学 
李可馨 浙江工商大学 
王美 浙江工商大学 
沈亚丽 浙江工商大学 
陈国文 浙江工商大学 
李欣 浙江工商大学 
中文摘要:利用玉米醇溶蛋白(zein)纳米粒子的运载功能,以阿拉伯胶(GA)为稳定剂,通过测定纳米粒子的平均粒径、zeta电位、吸光度等参数,研究GA—zein核壳结构对姜黄色素(Curcumin,cur)包埋率影响并探讨姜黄色素包埋后存在的形态。研究结果表明:zein在低质量浓度下形成均匀、分散的球状纳米粒子,随着zein质量浓度的增加,纳米粒子发生聚集、粘连、熔融等变形效果;当阿拉伯胶作为稳定剂,且添加量为0.3g时,GA—zein—cur分散体系最稳定;姜黄色素与zein质量比为1∶10时,GA—zein—cur纳米粒子最稳定,包埋率高达95.90%,形成了均一、稳定、透明度高的姜黄色素水溶液。
FU Yuying  LI Kexin  WANG Mei  SHEN Yali  CHEN Guowen  LI Xin
Zhejiang Gongshang University,Zhejiang Gongshang University,Zhejiang Gongshang University,Zhejiang Gongshang University,Zhejiang Gongshang University and Zhejiang Gongshang University
Key Words:zein  curcumin  GA  nanoparticles  embedding
Abstract:Influence of GA—zein core-shell structure on the curcumin embedding efficiency and status of curcumin after embedding treatment was investigated by taking advantage of the zein delivery functionality and stabilizing with Arabic gum, parameters such as mean particle diameters, zeta potential and absorbance were measured. The result showed that evenly dispersed globular nanoparticles were formulated under low zein concentration condition, as the increase of zein concentration, adhesion, aggregating and meltdown etc. transformation effects were occurred among the nanoparticles. It is necessary to add stabilizer to enhance the stability of zein delivery system. Stabilizing efficiency of different types of stabilizer were compared, and the result showed that stability of GA—zein—cur dispersed system reached peak when the system was stabilized with 0.3g Arabic gum;GA—zein—cur nanoparticles were the most stable when the quality ratio of curcumin and zein reached 1∶10, and the embedding efficiency was 95.90%, an even, stable and highly transparent curcumin aqueous solution was formulated.

Transactions of the Chinese Society for Agriculture Machinery (CSAM), in charged of China Association for Science and Technology (CAST), sponsored by CSAM and Chinese Academy of Agricultural Mechanization Science(CAAMS), started publication in 1957. It is the earliest interdisciplinary journal in Chinese which combines agricultural and engineering. It always closely grasps the development direction of agriculture engineering disciplines and the published papers represent the highest academic level of agriculture engineering in China. Currently, nearly 8,000 papers have been already published. There are around 3,000 papers contributed to the journal each year, but only around 600 of them will be accepted. Transactions of CSAM focuses on a wide range of agricultural machinery, irrigation, electronics, robotics, agro-products engineering, biological energy, agricultural structures and environment and more. Subjects in Transactions of the CSAM have been embodied by many internationally well-known index systems, such as: EI Compendex, CA, CSA, etc.

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