In order to decrease the damage and slippage of packaging material during the operation of conveying mechanism of freshcut fruit and vegetable packaging machine, a study was conducted. In this work, the compression deformation principle of the packaging boxes compressed by the conveying mechanism was analyzed. Through compression test of PET packaging boxes, the force of the conveying mechanism should be between 5N and 15N, and the compression displacement should be less than 10mm, which could avoid mechanical damage of packaging boxes and fruitvegetable products. Then, based on parametric modeling, the process and mechanism of the compression deformation of the packaging boxes were analyzed by the finite element simulation. The easy damage position of the packaging boxes and the reason were analyzed. According to the above experiment and analysis, the quality of packaging boxes, the compression displacement and the speed of the vertical belt conveyors were selected as the orthogonal test factors. When the quality of packaging boxes was 19g, the compression displacement between the vertical belt conveyors and the packaging boxes was 8mm and the speed of the vertical belt conveyors was 0.25m/s, the results showed that the slip rate was 0.043%. Under this condition, there was no compressed damage on packaging boxes and freshcut fruits and vegetables. Meanwhile, good transport synchronization was occurred between PET packaging boxes and conveying mechanism.