Beijing-Tianjin-Hebei Region is one of the most important developing regions in China, which relates to the national development strategy. The papers purpose is to analyze the fragmentation degree and artificial interference of the cultivated land. The space grid was taken as the basic unit and the density of cultivated land was calculated by kernel density function. And the density zoning was realized by natural breaks method. Then, the spatial distribution characteristics and the fragmentation degree of the cultivated land quantitatively were analyzed by using landscape pattern indexes. Finally, the direction of the consolidation of cultivated land was indicated by making a comparative analysis of the cultivated land fragmentation index and the artificial disturbance index. The results show that, the variation range of the density of cultivated land is 0~95.08points/km2, and more than 85% of the cultivated lands are distributed in the medium to high density region, centrally located in the central and southeastern of the region. The cultivated land area was decreased with the reduction of density value. The patch density, patch edge density, area weighted fractal dimension and the variation of the degree of aggregation in different density zones of the cultivated land all showed that, the fragmentation of the cultivated land was increased with the reduction of density value, but it was decreased with the reduction of density value in different density zones of artificial landscape. Both the degree of fragmentation and the degree of artificial disturbance were increased gradually with the increasing density value of cultivated land. And the human disturbance is the main factor to the increasing fragmentation in the region. Using kernel density function method can reflect the aggregation degree and the change characteristics of fragmentation of cultivated land more reasonably, and it can provide a reference for land consolidation and land use optimization in Beijing-Tianjin-Hebei Region.