Considering the nonlinear dynamic response of the greenhouse measurement and control system based on switch devices combination control, a discrete predictive model was proposed. The model had simple structure and uncomplex computation. Within the time domain not less than the maximum distribution delay of the system, the devices combination was keeped invariably and optimized rollingly to carry out predictive control, so the predictive control complexity of the system was greatly simplified, the problem of long distribution delays of the system was relieved. The simulation analysis and root mean square of the temperature showed that the optimization combination predictive control method was effective for the greenhouse measurement and control system with long distribution delays.