The ammonia nitrogen concentration in vinasse slurry is high, and the use of ammonia stripping technology to recover nitrogen nutrients has problems such as low utilization rate of alkali agent, poor gas-liquid contact effect and low ammonia absorption effect. In order to improve the ammonia recovery efficiency and process economy of vinasse slurry, the conditions of the vinasse slurry ammonia stripping process were optimized, and the effects of different temperatures, Ca(OH)2 dosage and filler types on ammonia stripping and acid absorption were explored. The influence of the operation effect of the integrated test device was evaluated, and the economical evaluation of the ammonia stripping process from the vinasse slurry was carried out. The results showed that the order of importance of influencing factors was obtained by orthogonal test was alkali dosage, air flow and temperature. The optimal process parameter combination was Ca(OH)2 dosage of 6.6g/L, gas flow of 6L/min and at a temperature of 52℃, the corresponding ammonia nitrogen removal rate was 99.0%; Ca(OH)2 had a good removal effect on SCOD and TP, and the corresponding SCOD and TP removal rates were 32.5% and 65.7% under the condition of 6.6g/L alkali dosage. The addition of Ca(OH)2 compared with the plan without alkali significantly improved the removal rates of ammonia nitrogen, TN, EC, SCOD and TP in the stripping process, reaching 97.4%~97.7%, 79.8%~84.2%, 68.3%~77.4%, 36.8%~45.3% and 77.1%~91.0%, respectively. The suitable anmonia stripping parameters are hacketten filler 37℃ and twice adding Ca(OH)2. The ammonia nitrogen removal rate reaches 97.4%, the effluent ammonia nitrogen concentration is as low as about 100mg/L, and the ammonia recovery amount reaches 1.22kg/m3. Compared with the scenario of no alkali addition and one-time alkali addition, the ammonia nitrogen removal rate can exceed 97% in the two-time alkali addition process scenario. The effluent ammonia nitrogen concentration was low (about 100mg/L), and the treatment cost was 9.75 yuan/m3, which had a relatively good economy. Therefore, ammonia stripping had good suitability for the treatment of scenario with high ammonia nitrogen concentration. The efficient recovery of nitrogen nutrients through ammonia stripping can relieve the pressure of biogas slurry farmland utilization, which was of great significance for the resource utilization of biogas slurry.