0.32％。 Resveratrol is a kind of bioactive substance with diverse biological activities. The technology of extracting resveratrol from the roots of peanuts was investigated with the yield of resveratrol as the guide. Ethanol was chosen as the extract solvent from four kinds of solvents. Based on single factor experiment, the extraction conditions were optimized by orthogonally rotational combination design. The optimum extraction conditions are as follows：the concentration of ethanol is 61.48%, the temperature is 69.97℃, the rate of solution to solid is 38.94mL/g, extraction time is 1h. and the number of extraction times is one. Under these optimized conditions, the yield of resveratrol is 0.32%.