Because the classic PID control doesn't satisfy the demand of automobile ABS in all conditions and it is short of an ability to identify road surface, fuzzy control is short of an ability to remove systemic stable error and it could not keep automobiles with higher control precisions. A dynamic mode of the wheels was built when an automobile was braking at first, aiming at automobile ABS and based on classic PID, a immune PID control algorithm was presented and used in automobile ABS system. Compared with the classic PID control algorithm and fuzzy control algorithm, the simulation result showed that the immune PID control algorithm has a shorter stabilization time, a smaller excess of system output, fewer response time and shorter braking distance, it is superior to the classic PID control algorithm and fuzzy control algorithm. The immune PID control algorithm has a higher application value.